The invention

Name of invention

Live-attenuated influenza vaccine with alpha-1,3-galactosyltransferase expression to enhance immune response

Vaccin antigrippal vivant atténué avec expression de l'alpha-1,3-galactosyltransférase pour amélioration de la réponse immunitaire

Invention description

Description

This is a live-attenuated influenza vaccine that leads to expression of α-Gal epitopes on the surface of infected cells. Anti-α-Gal antibodies facilitates the opsonization of these infected cells and enhances vaccine-induced immune responses.